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Common GLP-1-based medications include: Semaglutide (brand names: Wegovy, Ozempic) Tirzepatide (brand names: Zepbound, Mounjaro) Retatrutide (currently an investigational medication and not yet FDA-approved for weight loss) These medications work best when combined with a healthy diet, regular physical activity, and sustainable lifestyle changes
About 10% of people with PA test negative on PCA test
The use of measures of physical performance (for example, five times sit to stand) and muscle mass (for example, adjusting for weight rather than height squared) that take account of increased body mass should therefore be encouraged to facilitate inclusion of this patient group
Researchers explained that long-term high-fat, high-sugar diets can alter the lining of the duodenum, changing how the gut responds to food and affecting hormone production
No safety data exists for these populations
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